产品货号:
Z29129
中文名称:
TP1/TEP1抗体
英文名称:
Anti-TP1/TEP1 Antibody
产品规格:
0.1mg
发货周期:
1~3天
产品价格:
询价
抗体名称 | Anti-TP1/TEP1 Antibody |
指标别名 | TP1,TLP1,p240,TROVE1,VAULT2,TP1,Telomerase protein component 1,Telomerase-associated protein 1,Telomerase protein 1 |
克隆性 | Polyclonal |
检验物种 | human,mouse,rat |
应用范围 | ELISA,WB,IHC,IF |
基因名称 | TEP1 |
抗体来源 | Rabbit |
抗体类型 | IgG |
免疫原 | TP1 antibody was raised against a 20 amino acid synthetic peptide from near the amino terminus of human TP1.The immunogen is located within the first 50 amino acids of TP1. |
计算分子量 | 290kDa |
成分 | TP1 Antibody is supplied in PBS containing 0.02% sodium azide. |
纯化方式 | TP1 Antibody is affinity chromatography purified via peptide column. |
浓度 | 1mg/mL |
产品形态 | 溶液 |
保存条件 | 4℃可保存3个月,-20℃可保存1年。 |
背景资料 | Telomerase is an RNA-dependent DNA polymerase that uses an RNA component to add telomeric repeat sequences at the ends of chromosomes.Besides the RNA component which serves as the template that specifies the telomeric repeat,the telomerase complex contains a reverse transcriptase protein (TRT) and various accessory proteins including the telomerase-associated protein 1 (TP1).Telomerase activity is low in most somatic cells,causing the gradual shortening of telomeres which can ultimately lead to telomere fusion and cell death.High levels of telomerase activity are widely seen in cancerous cells and while recent experiments have suggested that telomerase may be a viable target in cancer therapy,expression levels of TP1 do not correlate with malignancy.At least two isoforms of TP1 are known to exist. |
Uniprot ID | Q99973 |
基因名全称 | Telomerase-associated protein 1 |
蛋白名全称 | Telomerase-associated protein 1 |
推荐稀释比 | TP1 antibody can be used for detection of TP1 by Western blot at 0.5 ~ 1μg/mL.Antibody can also be used for immunohistochemistry starting at 2.5μg/mL.For immunofluorescence start at 20μg/mL.Antibody validated:Western Blot in human samples;Immunohistochemistry in human samples and Immunofluorescence in human samples.All other applications and species not yet tested. |
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